How does the medication Colchicine for gout works? Colchicine is a toxic natural product extracted from the plants of the Colchicum genus. It has long been used to treat rheumatic problems especially gout and is still used for the same purpose nowadays despite the issues of its toxicity when taken in high dosages. Colchicine remains to being prescribed and used these days and is a mainstay in the treatment for gout.
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Colchicine For Gout
Colchicine for gout works by reducing uric acid deposition which leads to a reduction in the inflammatory response. Colchicine is not a pain killer but it reduces the pain in acute gout attacks. It is typically effective in relieving a gout attack within 12 to 24 hours. In low doses, colchicine reduces the chance of future gout attacks. Colchicine may be taken by some people who cannot take nonsteroidal- anti-inflammatory drugs (NSAIDS). Colchine may be given with other medications such as allopurinol(Zyloprim) or probenecid(Probalan)to help reduce the number and intensity of gout attacks when uric acid levels increase suddenly. Colchine is avoided or taken with caution by people who have a kidney or liver disease, bone marrow disorders, inflammatory bowel disease and a low white blood cell count. It is also risky to be taken by the elderly as well. It is really important that colchicines be prescribed carefully and appropriately by the doctor.
Side effects of Colchicine for Gout
Like any other medications, colchicine has side effects as well, these include nausea, vomiting, diarrhea, rashes and stomach cramps. Serious side effects of the medications are bone marrow problems and muscle inflammation and even damage to the kidneys and liver. It is important to pay attention about how the drug affects you and to report for any serious side effects. This way, dosages can be adjusted and to ensure that you are not overdosed by the drug. Over dosage of colchicine is dangerous and fatal.
Taking colchicine for gout needs adequate medical advice. Although it has proven to be very helpful in reducing gout attacks, it is still important for you to ask for advice and prescription from the doctor when taking colchicine for gout. This is to ensure that we get just the right dosage of the drug to be able to experience its therapeutic effects during gout attacks.
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